If you’ve tried all seven solutions and still see the error, your USB drive is likely incompatible. Purchase a budget-powered hard drive or invest in a high-quality SD card + USB adapter. The Wii’s legacy is too great to let a USB initialization error steal your GameCube and Wii library.
If you're still experiencing issues, try the following: wii usb loader gx usb device not initialized repack
Inside USB Loader GX:
If the loader sees a device but cannot talk to it, or sees nothing at all, it throws: If you’ve tried all seven solutions and still
38 -> Select cIOS Slot: 251 -> Press A to install. Once completed, exit back to the Homebrew Channel. Step 4: Adjust USB Loader GX Internal Settings If you're still experiencing issues, try the following:
Follow the Wii Hacks Guide to ensure your cIOS (d2x) is properly installed, specifically: cIOS 249 (base 56) cIOS 250 (base 57) cIOS 251 (base 58) 6. Check USB Loader GX Settings
If the hardware is correct but it still fails, you may need to reset the loader's settings.